Plasma exudation in the skin measured by external detection of conversion electrons
Identifieur interne : 000028 ( Main/Exploration ); précédent : 000027; suivant : 000029Plasma exudation in the skin measured by external detection of conversion electrons
Auteurs : RBID : ISTEX:259_1996_Article_BF00837627.pdfEnglish descriptors
- KwdEn :
Abstract
A novel technique for measurement of plasma exudation in the skin is described. Transferrin labelled in vivo with indium-113m is used as a plasma tracer. The conversion electrons from113mIn are detected with a polystyrene crystal mounted on a photomultiplier tube. Owing to the short range of the electrons in tissue, background radiation from tracer circulating in underlying tissue will be very small, allowing plasma exudation in the skin to be detected with a high signal to noise ratio. The characteristics of the detector system are described in model experiments using sheets of mylar to simulate soft tissue. The acute inflammatory response to histamine provocation was studied in guinea pig skin. A dose-related increase in count rate representing vasodilatation and plasma exudation was detected over the skin after histamine provocation. The electron radiation system appears suitable for detection of low levels of superficial radioactivity and for pathophysiological studies of the skin.
DOI: 10.1007/BF00837627
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title>Plasma exudation in the skin measured by external detection of conversion electrons</title><author><name>Angela Karambatsakidou</name><affiliation wicri:level="1"><mods:affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Radiophysics, Lund University Hospital, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name>Gösta Bergh</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Physiology, Malmö University Hospital, Malmö, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Physiology, Malmö University Hospital, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author><author><name>Lars Ahlgren</name><affiliation wicri:level="1"><mods:affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Radiophysics, Lund University Hospital, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name>Sven-Erik Strand</name><affiliation wicri:level="1"><mods:affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Radiophysics, Lund University Hospital, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name>Olle Olsson</name><affiliation wicri:level="1"><mods:affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Radiophysics, Lund University Hospital, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name>Lennart Greiff</name><affiliation wicri:level="1"><mods:affiliation> Department of Otorhinolaryngology, Lund University Hospital, Lund, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea> Department of Otorhinolaryngology, Lund University Hospital, Lund</wicri:regionArea><wicri:noRegion>Lund</wicri:noRegion></affiliation></author><author><name>Per Wollmer</name><affiliation wicri:level="1"><mods:affiliation>Department of Clinical Physiology, Malmö University Hospital, Malmö, Sweden</mods:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Physiology, Malmö University Hospital, Malmö</wicri:regionArea><wicri:noRegion>Malmö</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="RBID">ISTEX:259_1996_Article_BF00837627.pdf</idno><date when="1996">1996</date><idno type="doi">10.1007/BF00837627</idno><idno type="wicri:Area/Main/Corpus">000954</idno><idno type="wicri:Area/Main/Curation">000954</idno><idno type="wicri:Area/Main/Exploration">000028</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Guinea pig</term><term>Histamine</term><term>Indium-113m</term><term>Inflammation</term><term>Radionuclides</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="eng">A novel technique for measurement of plasma exudation in the skin is described. Transferrin labelled in vivo with indium-113m is used as a plasma tracer. The conversion electrons from113mIn are detected with a polystyrene crystal mounted on a photomultiplier tube. Owing to the short range of the electrons in tissue, background radiation from tracer circulating in underlying tissue will be very small, allowing plasma exudation in the skin to be detected with a high signal to noise ratio. The characteristics of the detector system are described in model experiments using sheets of mylar to simulate soft tissue. The acute inflammatory response to histamine provocation was studied in guinea pig skin. A dose-related increase in count rate representing vasodilatation and plasma exudation was detected over the skin after histamine provocation. The electron radiation system appears suitable for detection of low levels of superficial radioactivity and for pathophysiological studies of the skin.</div></front></TEI><mods xsi:schemaLocation="http://www.loc.gov/mods/v3 file:///applis/istex/home/loadistex/home/etc/xsd/mods.xsd" version="3.4" istexId="a7dbb559ab0a8a71d17902d02d648b65812966f7"><titleInfo lang="eng"><title>Plasma exudation in the skin measured by external detection of conversion electrons</title></titleInfo><name type="personal"><namePart type="given">Angela</namePart><namePart type="family">Karambatsakidou</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</affiliation></name><name type="personal"><namePart type="given">Gösta</namePart><namePart type="family">Bergh</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Clinical Physiology, Malmö University Hospital, Malmö, Sweden</affiliation></name><name type="personal"><namePart type="given">Lars</namePart><namePart type="family">Ahlgren</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</affiliation></name><name type="personal"><namePart type="given">Sven-Erik</namePart><namePart type="family">Strand</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</affiliation></name><name type="personal"><namePart type="given">Olle</namePart><namePart type="family">Olsson</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Radiophysics, Lund University Hospital, Lund, Sweden</affiliation></name><name type="personal"><namePart type="given">Lennart</namePart><namePart type="family">Greiff</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation> Department of Otorhinolaryngology, Lund University Hospital, Lund, Sweden</affiliation></name><name type="personal"><namePart type="given">Per</namePart><namePart type="family">Wollmer</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Department of Clinical Physiology, Malmö University Hospital, Malmö, Sweden</affiliation></name><typeOfResource>text</typeOfResource><genre>Original article</genre><genre>Original Paper</genre><originInfo><publisher>Springer-Verlag, Berlin/Heidelberg</publisher><dateCreated encoding="w3cdtf">1995-07-02</dateCreated><dateValid encoding="w3cdtf">2004-12-01</dateValid><copyrightDate encoding="w3cdtf">1996</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="eng">A novel technique for measurement of plasma exudation in the skin is described. Transferrin labelled in vivo with indium-113m is used as a plasma tracer. The conversion electrons from113mIn are detected with a polystyrene crystal mounted on a photomultiplier tube. Owing to the short range of the electrons in tissue, background radiation from tracer circulating in underlying tissue will be very small, allowing plasma exudation in the skin to be detected with a high signal to noise ratio. The characteristics of the detector system are described in model experiments using sheets of mylar to simulate soft tissue. The acute inflammatory response to histamine provocation was studied in guinea pig skin. A dose-related increase in count rate representing vasodilatation and plasma exudation was detected over the skin after histamine provocation. The electron radiation system appears suitable for detection of low levels of superficial radioactivity and for pathophysiological studies of the skin.</abstract><subject lang="eng"><genre>Key words</genre><topic>Histamine</topic><topic>Indium-113m</topic><topic>Inflammation</topic><topic>Radionuclides</topic><topic>Guinea pig</topic></subject><relatedItem type="series"><titleInfo type="abbreviated"><title>Eur J Nucl Med</title></titleInfo><titleInfo><title>European Journal of Nuclear Medicine</title><partNumber>Year: 1996</partNumber><partNumber>Volume: 23</partNumber><partNumber>Number: 3</partNumber></titleInfo><genre>Archive Journal</genre><originInfo><dateIssued encoding="w3cdtf">1996-03-01</dateIssued><copyrightDate encoding="w3cdtf">1996</copyrightDate></originInfo><subject usage="primary"><topic>Medicine & Public Health</topic><topic>Imaging / Radiology</topic><topic>Nuclear Medicine</topic></subject><identifier type="issn">0340-6997</identifier><identifier type="issn">Electronic: 1619-7089</identifier><identifier type="matrixNumber">259</identifier><identifier type="local">IssueArticleCount: 18</identifier><recordInfo><recordOrigin>Springer-Verlag, 1996</recordOrigin></recordInfo></relatedItem><identifier type="doi">10.1007/BF00837627</identifier><identifier type="matrixNumber">Art8</identifier><identifier type="local">BF00837627</identifier><accessCondition type="use and reproduction">MetadataGrant: OpenAccess</accessCondition><accessCondition type="use and reproduction">AbstractGrant: OpenAccess</accessCondition><accessCondition type="restriction on access">BodyPDFGrant: Restricted</accessCondition><accessCondition type="restriction on access">BodyHTMLGrant: Restricted</accessCondition><accessCondition type="restriction on access">BibliographyGrant: Restricted</accessCondition><accessCondition type="restriction on access">ESMGrant: Restricted</accessCondition><part><extent unit="pages"><start>290</start><end>294</end></extent></part><recordInfo><recordOrigin>Springer-Verlag, 1996</recordOrigin><recordIdentifier>259_1996_Article_BF00837627.pdf</recordIdentifier></recordInfo></mods></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=IndiumV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000028 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000028 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= *** parameter Area/wikiCode missing ***
|area= IndiumV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:259_1996_Article_BF00837627.pdf
|texte= Plasma exudation in the skin measured by external detection of conversion electrons
}}
| This area was generated with Dilib version V0.5.81. |  |